![]() ![]() This effort helped unify annotation efforts during the rise of high-throughput genome sequencing in the last decade.Īcross that same decade, synthetic biology has advanced capabilities for forward engineering of complex genetic systems with multiple sequence features. To address such concerns, the Sequence Ontology maintains a standard set of terms for describing different genetic features. ![]() ![]() A protein-coding DNA sequence might be called a coding sequence (CDS), an open reading frame, an exon, or simply a gene, depending on the organism and method of study. By the 1970s, molecular biologists had already developed many variations in the language used to describe functional regions of DNA, or genetic sequence features, with different terms used to describe similar features in different organisms. ![]()
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